Endoscopic gastric atrophy is strongly associated with gastric cancer development after Helicobacter pylori eradication

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A Possible Link between Gastric Mucosal Atrophy and Gastric Cancer after Helicobacter pylori Eradication

BACKGROUND The effect of H. pylori eradication in gastric cancer prevention can be attributed to the improvement of atrophic gastritis, which is a known risk of gastric cancer. However, gastric cancer has also been diagnosed after long-term H. pylori eradication. This study aimed to clarify the association between gastric atrophy and gastric cancer after H. pylori eradication, including its cli...

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Histological intestinal metaplasia and endoscopic atrophy are predictors of gastric cancer development after Helicobacter pylori eradication - Gastrointestinal Endoscopy

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Morphological Changes in Gastric Cancer after Helicobacter pylori Eradication Therapy

A 63-year-old Japanese woman visited her local doctor complaining of acid regurgitation. Esophagogastroduodenoscopy (EGD) revealed early gastric cancer and the patient was referred to our hospital. Physical examination and laboratory results, including serum carcinoembryonic antigen and cancer antigen 19-9, were unremarkable. EGD using indigo carmine dye in a chromoendoscopy revealed a protrudi...

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Helicobacter pylori and gastric atrophy--cancer paradoxes.

It has long been recognized that chronic gastritis is a precursor of gastric cancer only when atrophy is part of the spectrum of lesions (/). These observations are paradoxical, since atrophy is characterized by the loss of glandular epithelium, whereas cancer represents its excessive and anarchic replication. The phenomena that give rise to atrophy in the chronic gastritis complex are presentl...

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Helicobacter pylori Eradication Prevents Metachronous Gastric Neoplasms after Endoscopic Resection of Gastric Dysplasia

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ژورنال

عنوان ژورنال: Surgical Endoscopy

سال: 2016

ISSN: 0930-2794,1432-2218

DOI: 10.1007/s00464-016-5211-4